Doxycycline-induced esophagitis

Esophageal ulceration occasionally occurs in patients taking doxycycline capsules or tablets. We report two patients who develop acute esophageal ulceration after ingestion of doxycycline capsules for Acne vulgaris. Despite extensive investigation, no evidence of other causes was found. The ulcers are postulated to result from close contact between the capsules and the esophageal mucosa. We show the endoscopic image of the lesion, symptomatology, diagnosis, treatment, and prevention of doxycycline-induced esophageal lesions